Journal of Pharmacreations https://pharmacreations.com/jpc en-US editorpharmacreations@gmail.com (Dr.N.Sriram) editorpharmacreations@gmail.com (Dr.N.Sriram) Tue, 16 Jan 2024 17:30:12 +0000 OJS 3.2.1.4 http://blogs.law.harvard.edu/tech/rss 60 Formulations And In Vitro Evaluation Of Olmesartan Medoxilmil Floating Tablets https://pharmacreations.com/jpc/article/view/289 <p>In the present study the Olmesartan Medoxomil is a selective ACE-II blocking agent which is used in the treatment of hypertension. In this study Olmesartan Medoxomil tablets were prepared by usin fromg different polymers like HPMCK4M, HPMCK15M, HPMCK100M and CARBOPOL and HPC.</p> <p>15 formulations of floating tablets of Olmesartan Medoxomil were developed by direct compression technique. The F9 formulation was found to be best of all the trials showing that the drug release matches with the brand product.</p> <p>The best formulation F9 can successfully be employed as a controlled release floating drug delivery system. The floating tablets can control the fluctuations in the plasma drug concentration, increase the gastric residence time and eventually improve the bioavailability of the drug</p> Pinapa Sandeep Kumar, M. Rama Kotaiah Copyright (c) 2024 https://pharmacreations.com/jpc/article/view/289 Tue, 16 Jan 2024 00:00:00 +0000 WELLIA-R tablets; provides long lasting cerebral protection in brain tumor patients. https://pharmacreations.com/jpc/article/view/290 <p>Boswellia serrate extract in Wellia-R gained significant importance in treatment of cerebral edema in patients with brain tumors, colon cancer, lung cancer, blood cancer, skin cancer, breast cancer, renal cancer, fibro sarcoma, prostate cancer and pancreatic cancer. The medicinal properties of Boswellia serrate extract in Wellia-R have been known and utilized since antiquity. Its current potential as an anti inflammatory and anticancer agent are being investigated and hold great promise. This article reviews the current available scientific literature regarding the effect of wellia-R tablets, from Boswellia serrate extract that Provides long lasting cerebral protection in brain tumor patients.</p> Govind Shukla, Chandramauli, Balaswamy N.G , G. Lohitha, Rajkumar, C.J.Sampath Kumar Copyright (c) 2024 https://pharmacreations.com/jpc/article/view/290 Wed, 21 Feb 2024 00:00:00 +0000 Happi gummies Digestive Enzymes: helps to relief from occasional bloating & intestinal discomfort https://pharmacreations.com/jpc/article/view/291 <p>Gummy bears&nbsp;(German:&nbsp;<em>Gummibär</em>) are small,&nbsp;fruit gum&nbsp;candies, similar to a&nbsp;jelly baby. The candy is roughly 2&nbsp;cm (0.8&nbsp;in) long and shaped in the form of a&nbsp;bear. A modern healthy and fitness companion contain powerhouse ingredients to support a healthy lifestyle. Additionally, to Apple Cider Vinegar (including The Mother), it contains needed Vitamins &amp; Minerals. The Contemporary lifestyle behaviours of consuming processed foods and beverages will cause toxins within the body, and lowers immunity. Digestive Enzymes Indigestion, Bloating or gas, prevents you from enjoying a good meal then help is on the way. Now you have a safe natural and simple solution. Lactonova Happi gummy Digestive Enzymes helps your digestive system to break down the foods you consumed - so you receive all the nutrients available from your meals and halt the painful (and sometimes embarrassing) cycle of discomfort in intestine. Each Gummy goes to supplementing your own natural digestive enzymes -Contains a full spectrum of enzymes to help you digest carbohydrates, fats, and proteins Helps soothing your digestive system Lactonova Happi gummy Digestive Enzymes helps you relief from occasional bloating, intestinal discomfort and gas Help you obtain more nutritional value from the foods you consume. Contains natural enzymes at a high activity level than similar products on the market today. Simple and easy to take - one gummy immediately after meal.</p> GovindShukla, Chandramauli, N.G.Balaswamy, G.Lohitha, Rajkumar, C.J. Sampath Kumar Copyright (c) 2024 https://pharmacreations.com/jpc/article/view/291 Sat, 02 Mar 2024 00:00:00 +0000 Formulation And Evaluation Of Taste Masked Oral Disintegrating Tablets Of Atenolol https://pharmacreations.com/jpc/article/view/292 <p>In the present work, an attempt has been made to develop oral disintegrating tablets of Atenolol, was as Banana Powder, Primojel and Sodium starch glycolate was employed as super disintegrating agents to enhance the solubility and dissolution rate of drug molecule. The effects of disintegrants in different concentration on the release profile of Atenolol ODTs were studied. Developed ODTs were studied for their physicochemical properties and <em>in vitro</em> drug release profile. The studied parameters were found to be satisfactory for all ODT formulations of Atenolol. <em>In vitro</em> dissolution studies the formulation A3 consisting of Banana Powder was found be best among all the formulations it has exhibited faster disintegrating time (18 sec) when compared to other formulations and it showed 99.73 % drug release in 30min. FTIR studies proved that no chemical interaction between Atazanavir and superdisintegrants of the developed oral disintegrating tablets.</p> L. Prashanthi, V. Sushma, P. Munija Copyright (c) 2024 https://pharmacreations.com/jpc/article/view/292 Mon, 04 Mar 2024 00:00:00 +0000 Review on Betalains- Anti-Inflammatory activity https://pharmacreations.com/jpc/article/view/293 <p>Certain kinds of Caryophyllales plants and several higher-order fungi have betalains, which are naturally occurring colors based on nitrogen. Betalains are separated into betacyanins, which are red, and betaxanthins, which are yellow. It is commonly recognized that betalains have positive health effects and have a great capacity to scavenge free radicals, fight cancer, and prevent certain types of cancer. These characteristics open a recently popularized field of study: anti-inflammatory research<strong>.</strong> The significant potential of betalains as natural anti-inflammatory agents has been shown through in vitro, in vivo, and clinical investigations, leading to the conclusion that betalains have a good potential to promote health and can be utilized as an adjuvant therapy. Although the primary source of betalains is red beetroot, additional sources, such cactus plants, should be researched. The study on the anti-inflammatory effects of betalains is summarized in this article. The accumulating data indicates that a thorough investigation of betalains' anti-inflammatory properties is required.</p> V. Suresh kumar, S. Sravani, P. Tejaswini, Mohd. Muzaffer Hussain, Sehareesh Fathima, P. Munija Copyright (c) 2024 https://pharmacreations.com/jpc/article/view/293 Thu, 07 Mar 2024 00:00:00 +0000 Happy Multivit Gummies: A Comprehensive nutritive Gummy formula with 15 nutrients formulated to meet the demand of modern lifestyle. https://pharmacreations.com/jpc/article/view/294 <p>Gummy bears&nbsp;(German:&nbsp;<em>Gummibär</em>) are small,&nbsp;fruit gum&nbsp;candies, similar to a&nbsp;jelly baby. The candy is roughly 2&nbsp;cm (0.8&nbsp;in) long and shaped in the form of a&nbsp;bear.<strong> &nbsp;</strong>The present on-the-go lifestyle and high consumption of adulterated food products, it has now become difficult to obtain all the essential micronutrients from food alone. Supplementing with multivitamins may help us to bridge the dietary gaps caused due to unhealthy eating habits the fast-paced world, not only has our work shifted from physical work to more brain work, but also our diets have changed too. Consequently, unhealthy and fast-food diets have increased the demand for multivitamins. Happy Multivit Gummies is a comprehensive nutritive formula with 15 nutrients, especially formulated to meet the demands of modern life and provides support in the areas of health which are of most relevance.</p> GovindShukla, Chandramauli, BalaswamyN.G, G.Lohitha, Rajkumar, C.J. Sampath Kumar Copyright (c) 2024 https://pharmacreations.com/jpc/article/view/294 Wed, 10 Apr 2024 00:00:00 +0000