Main Article Content
Abstract
We intend to fabricatedrug loaded polymeric nanoparticles to overcome the limitations of curcumin in cancer treatment however, there are around eight reported methods to prepare polymeric nanoparticles. Selection of a appropriate method was a real challenge, as the selection of inappropriate method may lead to loss of resources. We used analytic hierarchy process in combination with data envelopment analysis method to select a appropriate nanoparticles preparation. Nanoprecipitation was identified as a appropriate method and implemented in the preparation of Curcumin loaded polymeric nanoparticles and the obtained nanoparticles were in the average particle size of 150 nm with polydispersity index of 0.2 and zeta potential of 30 mv. The study results concluded that the integration of analytical hierarchy process and data envelopment analysis has played a significant role in selecting a appropriate method for the nanoparticles preparation.