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Abstract
Phenothiazine derivatives have been synthesized and evaluated for their biological activities. A series of phenothiazine derivatives were synthesized using a facile and efficient method, and their structures were confirmed by spectroscopic analysis. The synthesized compounds were evaluated for their antimicrobial, antioxidant, and cytotoxic activities. The results showed that some of the synthesized compounds exhibited significant antimicrobial and antioxidant activities, while others showed promising cytotoxic activity against certain cancer cell lines. The structure-activity relationship (SAR) studies revealed that the presence of certain functional groups on the phenothiazine ring played a crucial role in determining the biological activities of the compounds. These findings suggest that phenothiazine derivatives could be potential lead compounds for the development of new drugs against various diseases.