Main Article Content
Abstract
Separation of Emtricitabine was successfully achieved Dona:YMC PACK PRO 150X4.6mm, 5µm, C18 or equivalenting an isocratic mode utilizing KH2PO4: Methanol(65:35) at a flowrate of 1.0mL/mins and eluate was monitored at 265nm, with a retention time of 3.150 minutes for Emtricitabine respectively. Assay Results 98.82%The specificity of the method shows good correlation between retention times of standard with the sample so, the method specifically determines the analyte in the sample without interference from excipients of tablet dosage forms. The method was extensively validated according to ICH guidelines for Assay.
Keywords
Emtricitabine
Method development
Validation