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The new coronavirus can harm the heart, kidneys, liver, and other organs, and 14 to 30 percent of COVID-19 patients in Wuhan have lost renal function, necessitating dialysis or kidney transplants. The new coronavirus infects people by targeting the ACE2 receptor on lung cells, which causes cytokine storms that harm human lungs, causing hyper inflammation and driving immune cells to kill healthy cells. This is why certain COVID-19 patients require specialized treatment. The liver produces proteins that protect the body from infections as a result of the inflammatory chemicals generated by COVID-19 infection. These proteins, on the other hand, can cause blood clotting, which can clog blood arteries in the heart and other organs, depriving the organs of oxygen and nutrition, leading to multiorgan failure and, eventually, acute lung damage, acute respiratory distress syndrome, and death. The effects of cytokine storm on bodily organs and management of cytokine storm in COVID-19 patients will be discussed in this review.