Formulation and evaluation of aripiprazole tablets for oral suspension

Abstract

      The present study is to develop and evaluate Aripiprazole (10 mg) tablet for oral suspension. Based on Literature survey and Compatibility Tests excipients like Microcrystalline Cellulose (pH 101), mannitol, crosscarmellose sodium, cross povidone, sodium starch glycolate, Magnesium Stearate were used.  In this present study, the tablets were prepared by using direct compression technique. In order to optimize the product, different formulations were developed. All the formulations were evaluated for physical characteristics, Disintegration, Dissolution studies. Based on the results of the above mentioned tests F–06 was selected as the best formulation as it showed total drug release with in 12 min than all other formulations.